Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 3/20 | 0.46 |
| ▸ | TDP2 | O95551 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | HAT1 | O14929 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743759 | 0.83 | MPO (0.43) | KDM4EMPOXDHRPS6KA3RPS6KA2 | |
| SCHEMBL1050380 | 0.82 | TMEM97 (0.47) | MEN1KMT2AUSP2RXFP1ALPL | |
| SCHEMBL12287118 | 0.79 | MEN1 (0.45) | MEN1KMT2AUSP2RXFP1ALPL | |
| SCHEMBL4748217 | 0.79 | TDP2 (0.62) | MEN1KMT2AUSP2RXFP1ALPL | |
| SCHEMBL15901239 | 0.78 | MEN1 (0.67) | MEN1KMT2AUSP2RXFP1ALPL | |
| SCHEMBL13496383 | 0.77 | MEN1 (0.61) | MEN1KMT2AUSP2RXFP1ALPL | |
| SCHEMBL12287155 | 0.76 | HAT1 (0.46) | MEN1KMT2AUSP2RXFP1ALPL | |
| SCHEMBL1965168 | 0.76 | CFTR (0.52) | KDM4EMPOXDHALDH1A1HPGD | |
| SCHEMBL12286897 | 0.76 | MEN1 (0.47) | MEN1KMT2AUSP2RXFP1ALPL | |
| SCHEMBL12286957 | 0.76 | MEN1 (0.59) | MEN1KMT2AUSP2RXFP1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |