Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | NGF | P01138 | 1/20 | 0.62 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | GSR | P00390 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL864918 | 0.81 | MEN1 (0.69) | TDP2MEN1KMT2AMAPTNGF | |
| SCHEMBL4747145 | 0.80 | GSR (0.55) | TDP2MEN1KMT2AMAPTNGF | |
| Lumiflavin SCHEMBL193713 | 0.80 | MEN1 (0.76) | TDP2MEN1KMT2AMAPTNGF | |
| Lumiflavin SCHEMBL29516802 | 0.80 | MEN1 (0.76) | TDP2MEN1KMT2AMAPTNGF | |
| SCHEMBL3476023 | 0.80 | GSR (0.65) | TDP2MEN1KMT2AMAPTNGF | |
| SCHEMBL4748228 | 0.80 | TDP2 (0.49) | TDP2MEN1KMT2AMAPTNGF | |
| SCHEMBL4747762 | 0.80 | TDP2 (0.49) | TDP2MEN1KMT2AMAPTNGF | |
| SCHEMBL4747662 | 0.80 | HRH4 (0.47) | TDP2MEN1KMT2AMAPTNGF | |
| SCHEMBL4747745 | 0.79 | MEN1 (0.48) | TDP2MEN1KMT2AMAPTNGF | |
| Lumiflavin SCHEMBL6365933 | 0.79 | MEN1 (0.74) | TDP2MEN1KMT2AMAPTNGF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |