Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 6/20 | 0.45 |
| ▸ | MPO | P05164 | 3/20 | 0.43 |
| ▸ | XDH | P47989 | 3/20 | 0.43 |
| ▸ | MAT2A | P31153 | 2/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743759 | 0.92 | MPO (0.43) | GSRMPOXDHMAT2ARPS6KA3 | |
| SCHEMBL4746265 | 0.86 | GSR (0.61) | GSRMPOXDHMAT2AKDM4E | |
| SCHEMBL4743788 | 0.86 | GSR (0.51) | GSRMPOXDHMAT2ARPS6KA3 | |
| SCHEMBL4747131 | 0.83 | DRD3 (0.39) | GSR | |
| SCHEMBL4744550 | 0.83 | TMEM97 (0.47) | GSRKDM4EALDH1A1HPGD | |
| SCHEMBL1965168 | 0.79 | CFTR (0.52) | MPOXDHKDM4EALDH1A1HPGD | |
| SCHEMBL4747855 | 0.76 | DRD3 (0.40) | — | |
| SCHEMBL4747745 | 0.75 | MEN1 (0.48) | GSRMPOXDHRPS6KA3RPS6KA2 | |
| SCHEMBL4746291 | 0.74 | TMEM97 (0.49) | GSR | |
| SCHEMBL4748220 | 0.74 | GSR (0.48) | GSRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |