Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.58 |
| ▸ | PPARG | P37231 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747119 | 0.98 | PPARA (0.59) | PPARAPPARGALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4744522 | 0.92 | PPARA (0.56) | PPARAPPARGALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4787982 | 0.91 | ALDH1A1 (0.54) | PPARAPPARGALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4743886 | 0.91 | POLB (0.58) | PPARAPPARGPOLBCD274MEN1 | |
| SCHEMBL4743964 | 0.89 | PPARA (0.57) | PPARAPPARGALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4743974 | 0.89 | PPARA (0.57) | PPARAPPARGALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4748393 | 0.88 | KDM4E (0.50) | PPARAPPARGALDH1A1KDM4E | |
| SCHEMBL4748486 | 0.88 | POLB (0.56) | PPARAPPARGPOLBCD274MEN1 | |
| SCHEMBL4744723 | 0.86 | PPARG (0.52) | PPARAPPARGALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4744720 | 0.86 | PPARG (0.52) | PPARAPPARGALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |