Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748106 | 0.81 | L3MBTL1 (0.41) | SMN1; SMN2RAB9AHPGDMEN1KMT2A | |
| SCHEMBL4748107 | 0.81 | F10 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4748099 | 0.78 | F10 (0.41) | SMN1; SMN2MEN1KMT2AF10TAAR1 | |
| SCHEMBL4751187 | 0.74 | SMPD1 (0.44) | F10 | |
| SCHEMBL2868546 | 0.71 | KMT2A (0.61) | SMN1; SMN2RAB9AKMT2ANR1H4NPC1 | |
| SCHEMBL2877777 | 0.69 | TDP1 (0.55) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL2874948 | 0.68 | RAB9A (0.56) | SMN1; SMN2RAB9AMEN1KMT2ANR1H4 | |
| SCHEMBL11326622 | 0.67 | KMT2A (0.41) | MEN1KMT2ATAAR1 | |
| SCHEMBL14044968 | 0.66 | GAA (0.44) | RAB9ALMNANPC1GAA | |
| SCHEMBL27712422 | 0.64 | RAB9A (0.44) | SMN1; SMN2RAB9AHPGDL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129129-A1 | HETEROCYCLIC PHENYL CARBAMATES AS NOVEL FAAH-INHIBITORS | KUOPION YLIOPISTO (FI) | 2008-10-30 | — | — | WO | disclosed |