Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | FLT3 | P36888 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | DAO | P14920 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580477 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1GAAMAPK1HSD17B10 | |
| SCHEMBL5279027 | 0.85 | KDM4E (0.74) | KDM4EALDH1A1GAAMAPK1HSD17B10 | |
| SCHEMBL721792 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1GAAMAPK1HSD17B10 | |
| SCHEMBL31081137 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1GAAMAPK1HSD17B10 | |
| SCHEMBL5164287 | 0.83 | KDM4E (0.71) | KDM4EALDH1A1GAAMAPK1HSD17B10 | |
| SCHEMBL1204954 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1GAAMAPK1HSD17B10 | |
| SCHEMBL1204956 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1GAAMAPK1HSD17B10 | |
| SCHEMBL23331084 | 0.82 | FLT3 (0.70) | KDM4EALDH1A1GAAMAPK1HSD17B10 | |
| SCHEMBL29354546 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1GAAMAPK1HSD17B10 | |
| SCHEMBL1254745 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1GAAMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059901-A | 1,3, 4-Oxadiazole compound and preparation method and application thereof | 成都大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122036615-A | Indazole hydrazide compound and preparation method and application thereof | 南京农业大学 | 2026-05-15 | — | — | CN | claimed |
| CN-117603188-A | Indole and quinoline skeleton-containing compound and application thereof | 苏州卫生职业技术学院 | 2024-02-27 | — | — | CN | claimed |
| CN-111349080-B | Indole acylhydrazone compound, preparation method thereof and application of indole acylhydrazone compound in prevention and treatment of plant diseases | 天津师范大学 | 2022-08-26 | — | — | CN | claimed |
| US-20210238204-A1 | INDOLE COMPOUNDS, PROCESS FOR THE PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2021-08-05 | — | — | US | claimed |
| EP-3793976-A1 | INDOLE COMPOUNDS, PROCESS FOR THE PREPARATION AND USE THEREOF | Council of Scientific & Industrial Research (IN) | 2021-03-24 | — | — | EP | claimed |
| CN-111349080-A | Indole acylhydrazone compound, preparation method thereof and application of indole acylhydrazone compound in prevention and treatment of plant diseases | 天津师范大学 | 2020-06-30 | — | — | CN | claimed |
| CN-111349038-A | Indolylhydrazone compounds, preparation method thereof and application thereof in preventing and treating plant diseases | 天津师范大学 | 2020-06-30 | — | — | CN | claimed |
| CN-110973144-A | Indole hydrazide-containing bactericidal composition | 京博农化科技有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-110896956-A | Indole hydrazide-containing bactericidal composition | 京博农化科技有限公司 | 2020-03-24 | — | — | CN | claimed |
| CN-104829597-B | 1H- indoles -2- carbohydrazide derivatives and its preparation method and application | 厦门大学 | 2018-07-17 | — | — | CN | claimed |
| CN-104860866-B | 5- (substitution carbon acylamino) -1H- indoles -2- carbohydrazide derivatives and its preparation method and application | 厦门大学 | 2018-07-17 | — | — | CN | claimed |
| WO-2002022576-A2 | 3-SUBSTITUTED INDOLE CARBOHYDRAZIDES USEFUL AS CELL PROLIFERATION AND ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-21 | — | — | WO | claimed |
| CN-122059901-A | 1,3, 4-Oxadiazole compound and preparation method and application thereof | 成都大学 | 2026-05-19 | — | — | CN | disclosed |
| US-12479805-B2 | Indazole hydrazide compound and application thereof | BEIJING BAHEAL CHENGCHUANG PHARMACEUTICAL RESEARCH AND DEVELOPMENT CO., LTD. (CN) | 2025-11-25 | — | — | US | disclosed |
| US-12479805-B2 | Indazole hydrazide compound and application thereof | BEIJING BAHEAL CHENGCHUANG PHARMACEUTICAL RESEARCH AND DEVELOPMENT CO., LTD. (CN) | 2025-11-25 | — | — | US | disclosed |
| US-6323228-B1 | INHIBITING ANGIOGENESIS IN A MAMMAL IN RECOGNIZED NEED OF SUCH TREATMENT COMPRISING ADMINISTERING TO THE MAMMAL WITH INDOLE SUBSTITUTED WITH HYDRAZIDES | ABBOTT LABORATORIES | 2001-11-27 | — | — | US | disclosed |
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238204-A1 | INDOLE COMPOUNDS, PROCESS FOR THE PREPARATION AND USE THEREOF | IDO1, IDO2, INMT | KDM4E 1740/4885ALDH1A1 1363/4885GAA 1895/4885 |
| US-12479805-B2 | Indazole hydrazide compound and application thereof | ITGB3, AR, HDAC3 | KDM4E 755/4885ALDH1A1 306/4885GAA 3704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.