Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647767 | 0.88 | MAPT (0.61) | LMNAMAPTKMT2AMEN1NQO2 | |
| SCHEMBL4250865 | 0.86 | LMNA (0.68) | LMNAMAPTKMT2AALDH1A1HSD17B10 | |
| SCHEMBL4744417 | 0.82 | KMT2A (0.47) | KMT2AMEN1GPR35GCKNQO2 | |
| SCHEMBL27890180 | 0.82 | ALDH1A1 (0.62) | KMT2AMEN1GPR35GCKNQO2 | |
| SCHEMBL317463 | 0.80 | LMNA (0.64) | LMNAMAPTKMT2AMEN1GPR35 | |
| Hydrochloric Acid SCHEMBL9732126 | 0.78 | LMNA (0.62) | LMNAMAPTKMT2AMEN1GPR35 | |
| SCHEMBL858917 | 0.73 | MAPT (0.56) | LMNAMAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL30572382 | 0.72 | LMNA (1.00) | LMNAMAPTKMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL4768081 | 0.72 | LMNA (1.00) | LMNAMAPTKMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL10824124 | 0.72 | LMNA (0.72) | LMNAMAPTCYP1A2TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117079-A1 | ANTIMICROBIAL COMPOUNDS BASED UPON 4-AMINOQUINOLINE | HELPERBY THERAPEUTICS LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |