Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GNG2 | P59768 | 1/20 | 0.46 |
| ▸ | GNB1 | P62873 | 1/20 | 0.46 |
| ▸ | GCK | P35557 | 2/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.45 |
| ▸ | NQO2 | P16083 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748820 | 0.88 | ALDH1A1 (0.66) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL439684 | 0.86 | NCF1 (0.59) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL4744417 | 0.82 | KMT2A (0.47) | ALDH1A1CASP1CASP7HSD17B10KMT2A | |
| SCHEMBL4748376 | 0.82 | LMNA (0.55) | ALDH1A1CASP1CASP7HSD17B10KMT2A | |
| SCHEMBL437286 | 0.80 | HSD17B10 (0.71) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL27906713 | 0.78 | ALDH1A1 (0.65) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL3792331 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL439264 | 0.78 | HSD17B10 (0.64) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL3471999 | 0.77 | ALDH1A1 (1.00) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL439655 | 0.76 | ALDH1A1 (0.80) | ALDH1A1CASP1CASP7HSD17B10NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933212-A | Novel combination and use | HELPERBY THERAPEUTICS LTD | 2013-02-13 | — | — | CN | claimed |
| CN-102933212-A | Novel combination and use | HELPERBY THERAPEUTICS LTD | 2013-02-13 | — | — | CN | disclosed |