Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653407 | 0.87 | CYP1A2 (0.54) | CYP2C19CYP1A2CYP2C9CYP2D6TSHR | |
| SCHEMBL24847549 | 0.87 | CYP1A2 (0.54) | CYP2C19CYP1A2CYP2C9CYP2D6TSHR | |
| SCHEMBL27959104 | 0.84 | PTPN1 (0.47) | CYP2C19CYP1A2CYP2C9CYP2D6TSHR | |
| SCHEMBL15506257 | 0.79 | IDO1 (0.55) | THRBIDO1GAAKMT2AMEN1 | |
| SCHEMBL402730 | 0.78 | CYP2D6 (0.47) | CYP2C19CYP1A2CYP2C9CYP2D6TSHR | |
| SCHEMBL4748455 | 0.76 | CA12 (0.57) | IDO1GAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL4418820 | 0.75 | LMNA (0.51) | CYP2C19CYP1A2CYP2C9TSHRLMNA | |
| SCHEMBL3068166 | 0.75 | CYP1A2 (0.48) | CYP2C19CYP1A2CYP2C9CYP2D6TSHR | |
| SCHEMBL27814147 | 0.75 | IDO1 (0.64) | SMN1; SMN2THRBIDO1GAAKMT2A | |
| SCHEMBL8843835 | 0.75 | ALDH1A1 (0.66) | LMNAGAAKMT2AMEN1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |