Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622917 | 0.88 | THRB (0.48) | CYP2D6CYP2C19CYP1A2CYP2C9TSHR | |
| SCHEMBL27770376 | 0.83 | HTT (0.51) | CYP2C19CYP1A2KMT2AALDH1A1LMNA | |
| SCHEMBL15506257 | 0.82 | IDO1 (0.55) | THRBIDO1GAAKMT2AMEN1 | |
| SCHEMBL4748433 | 0.78 | CYP2C19 (0.53) | CYP2D6CYP2C19CYP1A2CYP2C9TSHR | |
| SCHEMBL156664 | 0.77 | MEN1 (0.56) | THRBIDO1AKR1B1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL1252387 | 0.75 | MEN1 (0.54) | THRBIDO1AKR1B1GAAKMT2A | |
| Ammonia Solution, Strong SCHEMBL27486735 | 0.75 | MEN1 (0.54) | THRBIDO1AKR1B1GAAKMT2A | |
| SCHEMBL9509093 | 0.75 | LDHA (0.44) | CYP2D6CYP2C19TSHRALDH1A1LMNA | |
| SCHEMBL27959104 | 0.74 | PTPN1 (0.47) | CYP2D6CYP2C19CYP1A2CYP2C9TSHR | |
| SCHEMBL24847549 | 0.72 | CYP1A2 (0.54) | CYP2D6CYP2C19CYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150057283-A1 | REVERSE-TURN MIMETICS AND METHOD RELATING THERETO | CHOONGWAE PHARMA CORPORATION (KR) | 2015-02-26 | — | — | US | disclosed |
| US-8729262-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2014-05-20 | — | — | US | disclosed |
| US-8318738-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-11-27 | — | — | US | disclosed |
| US-8138337-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-03-20 | — | — | US | disclosed |
| US-8106049-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-01-31 | — | — | US | disclosed |
| US-8101751-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-01-24 | — | — | US | disclosed |
| US-20110294797-A1 | REVERSE-TURN MIMETICS AND METHOD RELATING THERETO | CHOONGWAE PHARMA CORPORATION (KR) | 2011-12-01 | — | — | US | disclosed |
| US-8049008-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2011-11-01 | — | — | US | disclosed |
| US-20110257185-A1 | REVERSE-TURN MIMETICS AND METHOD RELATING THERETO | CHOONGWAE PHARMA CORPORATION (KR) | 2011-10-20 | — | — | US | disclosed |
| US-7932384-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2011-04-26 | — | — | US | disclosed |
| CN-1872856-A | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-12-06 | — | — | CN | disclosed |
| CN-1871239-A | Modulation of beta-catenin/tcf-activated transcription | CHOONGWAE PHARMA CORP (KR) | 2006-11-29 | — | — | CN | disclosed |
| CN-1798746-A | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-07-05 | — | — | CN | disclosed |
| US-20060084655-A1 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2006-04-20 | — | — | US | disclosed |
| WO-2005116032-A2 | REVERSE-TURN MIMETICS AND METHOD RELATING THERETO | CHOONGWAE PHARMA CORPORATION (KR) | 2005-12-08 | — | — | WO | disclosed |
| US-20050059628-A1 | Modulation of beta-catenin/TCF-activated transcription | CHOONGWAE PHARMA CORPORATION (KR) | 2005-03-17 | — | — | US | disclosed |
| CN-1585770-A | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2005-02-23 | — | — | CN | disclosed |
| EP-1444235-A1 | REVERSE-TURN MIMETICS AND METHOD RELATING THERETO | Choongwae Pharma Corporation (KR) | 2004-08-11 | — | — | EP | disclosed |
| US-20040072831-A1 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2004-04-15 | — | — | US | disclosed |
| WO-2003031448-A1 | REVERSE-TURN MIMETICS AND METHOD RELATING THERETO | CHOONGWAE PHARMA CORPORATION (KR) | 2003-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084655-A1 | Reverse-turn mimetics and method relating thereto | WNT1, APC, WNT3 | CYP2D6 4684/4885CYP2C19 4819/4885CYP1A2 4837/4885 |
| US-20150057283-A1 | REVERSE-TURN MIMETICS AND METHOD RELATING THERETO | WNT1, APC, WNT3 | CYP2D6 4684/4885CYP2C19 4819/4885CYP1A2 4837/4885 |
| US-20110257185-A1 | REVERSE-TURN MIMETICS AND METHOD RELATING THERETO | WNT1, APC, WNT3 | CYP2D6 4684/4885CYP2C19 4819/4885CYP1A2 4837/4885 |
| US-20050059628-A1 | Modulation of beta-catenin/TCF-activated transcription | TCF4, TCF7, TCF7L2 | CYP2D6 4469/4885CYP2C19 4857/4885CYP1A2 4121/4885 |
| US-20110294797-A1 | REVERSE-TURN MIMETICS AND METHOD RELATING THERETO | WNT1, APC, WNT3 | CYP2D6 4684/4885CYP2C19 4819/4885CYP1A2 4837/4885 |
| US-20040072831-A1 | Reverse-turn mimetics and method relating thereto | WNT1, APC, WNT3 | CYP2D6 4678/4885CYP2C19 4818/4885CYP1A2 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.