SCHEMBL474661

SCHEMBL474661

C#Cc1ccc(NC(C)=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.70
MEN1 O00255 4/20 0.70
SMN1; SMN2 Q16637 3/20 0.70
ALDH1A1 P00352 2/20 0.70
RAB9A P51151 2/20 0.70
KDM4E B2RXH2 1/20 0.70
HPGD P15428 1/20 0.70
CYP2C19 P33261 1/20 0.70
HTT P42858 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
MAPT P10636 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
CA12 O43570 1/20 0.57
BRD4 O60885 1/20 0.57
NR1I2 O75469 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
MB P02144 1/20 0.57
CYP1A1 P04798 1/20 0.57
CA3 P07451 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9771269 0.98 KMT2A (0.68) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL4748577 0.83 CYP2C9 (0.56) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL861674 0.82 SMN1; SMN2 (0.84) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL17792928 0.81 RXFP1 (0.57) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL8319331 0.81 CYP2C9 (0.50) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL599684 0.81 KMT2A (0.73) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL31193370 0.81 MAPT (0.68) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL1542345 0.80 ALDH1A1 (0.58) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL14508151 0.79 ALDH1A1 (0.46) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL17055695 0.79 SMN1; SMN2 (0.44) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396313-A Alkenyl borate, and preparation method and application thereof 中山大学 2023-07-07 CN claimed
US-9868820-B2 Polyarylene materials ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-01-16 US claimed
EP-4663628-A1 NEW COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Samjin Pharmaceutical Co., Ltd. (KR) 2025-12-17 EP disclosed
US-12379660-B2 Adhesion promoting photoresist underlayer composition DUPONT ELECTRONIC MATERIALS INTERNATIONAL, LLC (US) 2025-08-05 US disclosed
US-20250136580-A1 INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2025-05-01 US disclosed
WO-2025048243-A1 NOVEL ISOXAZOLE COMPOUND AS TM4SF5-SPECIFIC INHIBITOR AND USE THEREOF 서울대학교산학협력단 2025-03-06 WO disclosed
WO-2024166024-A1 NEW COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 삼진제약주식회사 2024-08-15 WO disclosed
CN-116396313-A Alkenyl borate, and preparation method and application thereof 中山大学 2023-07-07 CN disclosed
US-20220356182-A1 INHIBITORS OF HEPATITIS C VIRUS REPLICATION MERCK SHARP & DOHME CORP. (US) 2022-11-10 US disclosed
US-20220356182-A1 INHIBITORS OF HEPATITIS C VIRUS REPLICATION MERCK SHARP & DOHME CORP. (US) 2022-11-10 US disclosed
CN-114671874-A Theophylline acetic acid derivative with anti-tumor activity and preparation method and application thereof 济南爱思医药科技有限公司 2022-06-28 CN disclosed
EP-0200011-B1 HEAT-DEVELOPABLE LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-09-13 EP disclosed
US-4857961-A Image forming apparatus FUJI PHOTO FILM CO., LTD. (JP) 1989-08-15 US disclosed
US-4782004-A PHENOLIC SULFONAMIDE OR POLYMER WITH PHENOL AND/OR SULFONAMIDE GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1988-11-01 US disclosed
US-4775613-A CONTAINING ACETYLENE SILVER COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1988-10-04 US disclosed
US-4761361-A SILVER HALIDE EMULSIONS FUJI PHOTO FILM CO., LTD. (JP) 1988-08-02 US disclosed
US-4745043-A PHOTOGRAPHY, SILVER HALIDE EMULSIONS FUJI PHOTO FILM CO., LTD. (JP) 1988-05-17 US disclosed
US-4740445-A COMPLEXING METAL COMPOUNDS WITH PYRIDINE OR QUINOLINE RING HAVING AMINE SALT FUNCTION FUJI PHOTO FILM CO., LTD. (JP) 1988-04-26 US disclosed
EP-0210660-A2 Image forming process FUJI PHOTO FILM CO., LTD. (JP) 1987-02-04 EP disclosed
EP-0200011-A1 Heat-developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-11-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356182-A1 INHIBITORS OF HEPATITIS C VIRUS REPLICATION HAVCR2, HCCS, EIF2AK2 KMT2A 4309/4885MEN1 4685/4885SMN1; SMN2 4833/4885
US-20250136580-A1 INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE MELK, HIPK1, HIPK3 KMT2A 1029/4885MEN1 3710/4885SMN1; SMN2 3069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.