Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748577 | 0.84 | CYP2C9 (0.56) | CYP2C9MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL13379288 | 0.83 | PTPN11 (0.61) | PTPN11 | |
| SCHEMBL3309759 | 0.82 | PTPN11 (0.59) | PTPN11 | |
| SCHEMBL17424508 | 0.82 | CYP2C9 (0.67) | CYP2C9MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL474661 | 0.81 | KMT2A (0.70) | MEN1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL4552493 | 0.81 | PEPD (0.57) | CYP2C9MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL10778839 | 0.81 | SMN1; SMN2 (0.52) | KMT2ARAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL13950464 | 0.80 | POLB (0.46) | CYP2C9MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9771269 | 0.79 | KMT2A (0.68) | MEN1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL4312329 | 0.79 | NPC1 (0.57) | MEN1KMT2AKDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4741383-A1 | COMPOUND AND USE THEREOF AS ANTI-CANCER DRUG | Tyligand Bioscience (Shanghai) Limited (CN) | 2026-05-13 | — | — | EP | disclosed |
| WO-2024083111-A1 | NOVEL HETEROCYCLIC COMPOUNDS | 首药控股(北京)股份有限公司 | 2024-04-25 | — | — | WO | disclosed |
| WO-2024008033-A1 | CLASS OF 7-((FIVE-MEMBERED HETEROCYCLIC)METHYL)-8-CARBOXYLIC ACID-BENZO CYCLIC BORATE DERIVATIVES AND USES THEREOF | 福安药业集团重庆三禾兴医药科技有限公司 | 2024-01-11 | — | — | WO | disclosed |
| EP-3625218-B1 | PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| US-10947186-B2 | Process for hydrocyanation of terminal alkynes | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-03-16 | — | — | US | disclosed |
| US-20200181068-A1 | PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2020-06-11 | — | — | US | disclosed |
| EP-3625218-A1 | PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES | Studiengesellschaft Kohle mbH (DE) | 2020-03-25 | — | — | EP | disclosed |
| WO-2018210631-A1 | PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2018-11-22 | — | — | WO | disclosed |
| EP-3127900-B1 | ALKYNYL INDAZOLE DERIVATIVE AND USE THEREOF | SENJU PHARMA CO (JP) | 2017-10-18 | — | — | EP | disclosed |
| US-9617222-B1 | Alkynyl indazole derivative and use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2017-04-11 | — | — | US | disclosed |
| US-20170096400-A1 | ALKYNYL INDAZOLE DERIVATIVE AND USE THEREOF | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2017-04-06 | — | — | US | disclosed |
| EP-3127900-A1 | ALKYNYL INDAZOLE DERIVATIVE AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 2017-02-08 | — | — | EP | disclosed |
| US-8748412-B2 | Phenylalanine derivatives and their use as non-peptide GLP-1 receptor modulators | ARGUSINA BIOSCIENCE INC. (KY) | 2014-06-10 | — | — | US | disclosed |
| EP-2531198-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | Argusina Inc. (US) | 2012-12-12 | — | — | EP | disclosed |
| EP-1597244-B1 | ETHYNYL DERIVATIVES SERVING AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2010-07-07 | — | — | EP | disclosed |
| WO-2004076429-A1 | ETHYNYL DERIVATIVES SERVING AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181068-A1 | PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES | ALKBH3, ALKBH2, ALKBH5 | CYP2C9 978/4885MEN1 2865/4885KMT2A 507/4885 |
| US-10947186-B2 | Process for hydrocyanation of terminal alkynes | ALKBH3, ALKBH2, ALKBH5 | CYP2C9 978/4885MEN1 2865/4885KMT2A 507/4885 |
| US-20170096400-A1 | ALKYNYL INDAZOLE DERIVATIVE AND USE THEREOF | KDR, FLT1, FLT4 | CYP2C9 2973/4885MEN1 4422/4885KMT2A 4546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.