SCHEMBL4748741

SCHEMBL4748741

Nc1cc2c(cc1N)NC(=O)[N]2

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2719624 0.74 HCAR2 (0.30)
SCHEMBL3826696 0.74 GRM5 (0.30)
SCHEMBL4752422 0.67 CES1 (0.44) CYP3A4
SCHEMBL4753132 0.67 TGM2 (0.44)
SCHEMBL4382993 0.67 TGM2 (0.44) CYP3A4BLM
SCHEMBL2719976 0.67 CES1 (0.44)
SCHEMBL8556761 0.66 CES1 (0.38)
SCHEMBL31436321 0.64 PTK2 (0.50) CYP3A4BLM
SCHEMBL6120237 0.63 PARP1 (0.33) CYP3A4BLM
SCHEMBL3351240 0.60 PDE3B (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008136841-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-11-13 WO disclosed