Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.67 |
| ▸ | CTSL | P07711 | 2/20 | 0.67 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.61 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 1/20 | 0.59 |
| ▸ | RXRB | P28702 | 1/20 | 0.59 |
| ▸ | RXRG | P48443 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27322834 | 0.90 | MAOB (0.67) | CTSVCTSLNR4A2SMN1; SMN2NR1H4 | |
| SCHEMBL6098127 | 0.87 | CTSV (0.65) | CTSVCTSLNR4A2SIRT2MEN1 | |
| SCHEMBL14044001 | 0.83 | FFAR1 (0.79) | SRD5A2NR4A2TSHRSMN1; SMN2NR1H4 | |
| SCHEMBL6359813 | 0.82 | CTSV (0.56) | CTSVCTSLNR4A2SMN1; SMN2SIRT2 | |
| SCHEMBL27438029 | 0.82 | CTSV (0.56) | CTSVCTSLNR1H4SIRT2MEN1 | |
| SCHEMBL27438020 | 0.82 | MAOB (0.62) | CTSVCTSLSMN1; SMN2SIRT2MEN1 | |
| SCHEMBL1123461 | 0.81 | NR4A2 (0.81) | SRD5A2NR4A2TSHRSMN1; SMN2FFAR1 | |
| SCHEMBL14043910 | 0.81 | AKR1C3 (0.60) | SRD5A2NR1H4SIRT2POLBNPC1 | |
| SCHEMBL27429206 | 0.81 | MAOA (0.65) | CTSVCTSLSIRT2MEN1KMT2A | |
| SCHEMBL10983488 | 0.80 | CTSV (1.00) | CTSVCTSLNR4A2TSHRNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121570-A1 | COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008121570-A1 | COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2008-10-09 | — | — | WO | disclosed |