Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748870 | 0.91 | PGR (0.40) | PGRMAPTP2RY12CYP2C9GPR119 | |
| SCHEMBL4607965 | 0.86 | PGR (0.42) | PGRMRGPRX4HCRTR2 | |
| SCHEMBL4609500 | 0.85 | PGR (0.46) | PGRMRGPRX4HCRTR2 | |
| SCHEMBL14021476 | 0.85 | KDM4E (0.36) | PGRMAPTKDM4EGPR119HSD17B10 | |
| SCHEMBL4752244 | 0.85 | PGR (0.39) | PGRMRGPRX4HCRTR2 | |
| SCHEMBL4748816 | 0.81 | PGR (0.36) | PGRMRGPRX4HCRTR2 | |
| SCHEMBL4884834 | 0.80 | PGR (0.36) | PGRMRGPRX4HCRTR2 | |
| SCHEMBL4962986 | 0.80 | ATM (0.41) | PGRMAPTKDM4EMRGPRX4HSD17B10 | |
| SCHEMBL4751693 | 0.79 | DHODH (0.39) | MAPTKDM4EGPR119DHODHHSD17B10 | |
| SCHEMBL4976120 | 0.79 | PGR (0.46) | PGRMRGPRX4HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |