Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.40 |
| ▸ | AR | P10275 | 8/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748844 | 0.91 | PGR (0.38) | PGRGPR119MAPTDHODHCYP2C9 | |
| SCHEMBL4978023 | 0.85 | PGR (0.45) | PGRARSLC22A12 | |
| SCHEMBL4751018 | 0.84 | PGR (0.43) | PGRARKDRSLC22A12 | |
| SCHEMBL14021476 | 0.80 | KDM4E (0.36) | PGRGPR119MAPT | |
| SCHEMBL14021725 | 0.80 | PGR (0.39) | PGRARKDRSLC22A12 | |
| SCHEMBL4607965 | 0.77 | PGR (0.42) | PGRARKDRSLC22A12 | |
| SCHEMBL4947332 | 0.77 | PGR (0.38) | PGRARKDRSLC22A12 | |
| SCHEMBL4752256 | 0.77 | AR (0.39) | PGRARGPR119KDRCYP11B2 | |
| SCHEMBL4609500 | 0.77 | PGR (0.46) | PGRARKDRSLC22A12 | |
| SCHEMBL4752244 | 0.76 | PGR (0.39) | PGRARKDRSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |