Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752244 | 0.88 | PGR (0.39) | PGRKDRHCRTR2MRGPRX4SLC22A12 | |
| SCHEMBL4947332 | 0.88 | PGR (0.38) | PGRKDRSLC22A12 | |
| SCHEMBL4888214 | 0.86 | PGR (0.32) | PGRDPP4KCNH2 | |
| SCHEMBL4789550 | 0.85 | PGR (0.34) | PGRKDRMRGPRX4DPP4KCNH2 | |
| SCHEMBL4748816 | 0.84 | PGR (0.36) | PGRKDRHCRTR2MRGPRX4SLC22A12 | |
| SCHEMBL4607965 | 0.84 | PGR (0.42) | PGRKDRHCRTR2MRGPRX4SLC22A12 | |
| SCHEMBL4609500 | 0.83 | PGR (0.46) | PGRKDRHCRTR2MRGPRX4SLC22A12 | |
| SCHEMBL4748844 | 0.80 | PGR (0.38) | PGRHCRTR2MRGPRX4 | |
| SCHEMBL14021725 | 0.79 | PGR (0.39) | PGRKDRSLC22A12 | |
| SCHEMBL4751018 | 0.78 | PGR (0.43) | PGRKDRSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |