Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751788 | 0.86 | AKR1C3 (0.36) | AKR1C3AKR1C2MEN1KMT2AFFAR1 | |
| SCHEMBL5831309 | 0.72 | XDH (0.41) | AKR1C3AKR1C2MEN1KMT2AKDM4E | |
| SCHEMBL11786434 | 0.72 | XDH (0.41) | AKR1C3AKR1C2MEN1KMT2AKDM4E | |
| SCHEMBL4748909 | 0.71 | BACE1 (0.36) | AKR1C3AKR1C2MEN1KMT2APTGS2 | |
| SCHEMBL4751790 | 0.66 | BACE1 (0.36) | AKR1C3AKR1C2MAPT | |
| SCHEMBL1176840 | 0.66 | POLB (0.39) | AKR1C3AKR1C2MEN1KMT2AKDM4E | |
| SCHEMBL10633163 | 0.65 | MAPT (0.48) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL1176614 | 0.65 | ALDH1A1 (0.45) | AKR1C3AKR1C2MEN1KMT2APTGS2 | |
| SCHEMBL18614934 | 0.62 | MRGPRX4 (0.49) | AKR1C3AKR1C2PPARA | |
| SCHEMBL22017029 | 0.62 | XDH (0.37) | AKR1C3AKR1C2MEN1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135488-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2008-11-13 | — | — | WO | disclosed |