Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751790 | 0.85 | BACE1 (0.36) | BACE1MRGPRX4RXRAAKR1C3AKR1C2 | |
| SCHEMBL7946697 | 0.75 | BACE1 (0.34) | BACE1RXRANR4A2 | |
| SCHEMBL11786434 | 0.73 | XDH (0.41) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL5831309 | 0.73 | XDH (0.41) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL4748907 | 0.71 | AKR1C3 (0.34) | PTGS2AKR1C3AKR1C2MAPTMEN1 | |
| SCHEMBL21104531 | 0.70 | KMT2A (0.46) | MAPTMEN1KMT2AALDH1A1TAS2R14 | |
| SCHEMBL8155821 | 0.68 | BACE1 (0.41) | BACE1 | |
| SCHEMBL1176840 | 0.67 | POLB (0.39) | MRGPRX4AKR1C3AKR1C2MAPTMEN1 | |
| SCHEMBL10633163 | 0.66 | MAPT (0.48) | MRGPRX4RXRAMAPTMEN1KMT2A | |
| SCHEMBL4751788 | 0.66 | AKR1C3 (0.36) | AKR1C3AKR1C2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135488-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2008-11-13 | — | — | WO | disclosed |