Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346038 | 0.77 | TTR (0.35) | BACE1 | |
| SCHEMBL4748909 | 0.75 | BACE1 (0.36) | BACE1RXRANR4A2 | |
| SCHEMBL7875993 | 0.72 | HCAR3 (0.43) | BACE1 | |
| SCHEMBL3478647 | 0.72 | HCAR3 (0.43) | BACE1 | |
| SCHEMBL7880963 | 0.71 | BACE1 (0.42) | BACE1 | |
| SCHEMBL7880567 | 0.71 | BACE1 (0.37) | BACE1 | |
| SCHEMBL7875893 | 0.71 | BACE1 (0.59) | BACE1 | |
| SCHEMBL3469031 | 0.71 | BACE1 (0.41) | BACE1 | |
| SCHEMBL3350177 | 0.70 | KDM4C (0.44) | — | |
| SCHEMBL2210348 | 0.68 | BACE1 (0.64) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |