Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
| ▸ | GABRE | P78334 | 2/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306591 | 0.89 | CA1 (0.37) | CA2CA1TSHR | |
| SCHEMBL1685420 | 0.88 | — | — | |
| SCHEMBL6369370 | 0.87 | ALOX15 (0.43) | CA2CA1GABRPGABRDGABRA1 | |
| SCHEMBL10431485 | 0.87 | CA1 (0.35) | CA2CA1 | |
| SCHEMBL10776270 | 0.87 | CA2 (0.50) | CA2CA1TSHRNFKB1CYP3A4 | |
| SCHEMBL1231804 | 0.85 | CA1 (0.43) | CA2CA1BLMPMP22 | |
| SCHEMBL1230306 | 0.84 | CA1 (0.37) | CA2CA1BLMPMP22 | |
| SCHEMBL4255669 | 0.84 | — | — | |
| SCHEMBL28059222 | 0.84 | — | — | |
| SCHEMBL2583977 | 0.83 | CA1 (0.42) | CA2CA1CYP1A2CYP3A4BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-A | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | claimed |
| US-4543371-A | Polymeric compositions and hydrogels formed therefrom | SYNTEX (U.S.A.) INC. (US) | 1985-09-24 | — | — | US | claimed |
| US-4379864-A | Polymeric compositions and hydrogels formed therefrom | SYNTEX (U.S.A.) INC. (US) | 1983-04-12 | — | — | US | claimed |
| US-4267295-A | Polymeric compositions and hydrogels formed therefrom | SYNTEX (U.S.A.) INC. (US) | 1981-05-12 | — | — | US | claimed |
| EP-4077273-A1 | ALDIMINES AND USES THEREOF | Bostik SA (FR) | 2022-10-26 | — | — | EP | disclosed |
| CN-109563043-A | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-106794682-B | Coated-body | 大日本涂料株式会社 | 2018-09-18 | — | — | CN | disclosed |
| CN-106794682-A | Coated-body | 大日本涂料株式会社 | 2017-05-31 | — | — | CN | disclosed |
| CN-106164068-A | Isoindolinone compounds as the GPR119 regulator for the treatment of diabetes, obesity, dyslipidemia and associated conditions | 赛诺菲 | 2016-11-23 | — | — | CN | disclosed |
| CN-106118196-A | Powder coating composition and manufacture method thereof | 大日本涂料株式会社 | 2016-11-16 | — | — | CN | disclosed |
| EP-3041895-A1 | ICI THICKENER COMPOSITION AND USES | Elementis Specialties, Inc. (US) | 2016-07-13 | — | — | EP | disclosed |
| EP-2112206-B1 | Polymer Composition | ROHM & HAAS (US) | 2016-06-29 | — | — | EP | disclosed |
| US-4338419-A | REDUCING IRRITATION FROW WEARING CONTACT LENSES | SYNTEX (U.S.A.) INC. (US) | 1982-07-06 | — | — | US | disclosed |
| US-4290812-A | Process for the production of inks free of foreign salts | OLYMPIA WERKE AG (DE) | 1981-09-22 | — | — | US | disclosed |
| EP-0032905-A4 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS. | FOLEY WILLIAM M JUN | 1981-08-27 | — | — | EP | disclosed |
| EP-0032905-A1 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS | FOLEY, Jr., William M. (US) | 1981-08-05 | — | — | EP | disclosed |
| US-4267295-A | Polymeric compositions and hydrogels formed therefrom | SYNTEX (U.S.A.) INC. (US) | 1981-05-12 | — | — | US | disclosed |
| WO-1980002840-A1 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS | FOLEY W | 1980-12-24 | — | — | WO | disclosed |
| US-4180308-A | Contact lens | SYNTEX (USA) INC. (US) | 1979-12-25 | — | — | US | disclosed |
| US-4056496-A | ACRYLIC | CORNEAL SCIENCES, INC. (US) | 1977-11-01 | — | — | US | disclosed |