SCHEMBL8306591

SCHEMBL8306591

NCCC(CCO)C(N)=O

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
GABRR1 P24046 2/20 0.36
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
CPB2 Q96IY4 1/20 0.31
GABBR2 O75899 1/20 0.30
GABBR1 Q9UBS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL474901 0.89 CA2 (0.42) CA1CA2TSHR
SCHEMBL29100382 0.80 GABRR1 (0.46) GABRR1CPB2
SCHEMBL1685420 0.79
SCHEMBL10431485 0.78 CA1 (0.35) CA1CA2
SCHEMBL10776270 0.78 CA2 (0.50) CA1CA2ALDH1A1TSHR
SCHEMBL6369370 0.78 ALOX15 (0.43) CA1CA2
SCHEMBL7859211 0.78 CA2 (0.50) CA1CA2GABRR1TSHRGABBR2
SCHEMBL17365610 0.76 FOLH1 (0.46) GABRR1TSHRGABBR2GABBR1
SCHEMBL5892045 0.76 FOLH1 (0.46) GABRR1TSHRGABBR2GABBR1
SCHEMBL1231804 0.76 CA1 (0.43) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005026163-A1 DIOXOLANE DERIVATIVES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2005-03-24 WO disclosed