Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.32 |
| ▸ | NOS2 | P35228 | 4/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278247 | 0.74 | — | — | |
| SCHEMBL4511579 | 0.73 | NOS1 (0.33) | NOS1NOS2ALDH1A1 | |
| SCHEMBL9679332 | 0.73 | ADH1B (0.41) | NOS1NOS2 | |
| SCHEMBL7784142 | 0.72 | NOS2 (0.47) | NOS1NOS2NOS3 | |
| SCHEMBL10475292 | 0.71 | ADH1B (0.46) | ALDH1A1DRD1 | |
| SCHEMBL2349446 | 0.70 | — | — | |
| SCHEMBL5545183 | 0.70 | ADH1B (0.50) | ALDH1A1DRD1 | |
| SCHEMBL10470902 | 0.68 | — | — | |
| SCHEMBL7125781 | 0.68 | SAT1 (0.32) | — | |
| SCHEMBL7125784 | 0.68 | SAT1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124582-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |