Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749434 | 0.93 | SCN9A (0.33) | SLC6A1MEN1KMT2ASCN9AKIF11 | |
| SCHEMBL4749467 | 0.91 | KIF11 (0.34) | SLC6A1SCN9AKIF11ALDH1A1ACHE | |
| SCHEMBL4751838 | 0.91 | KIF11 (0.34) | SLC6A1SCN9AKIF11ALDH1A1ACHE | |
| SCHEMBL4749462 | 0.91 | KIF11 (0.34) | SLC6A1SCN9AKIF11ALDH1A1ACHE | |
| SCHEMBL4749435 | 0.91 | KIF11 (0.34) | SLC6A1SCN9AKIF11ALDH1A1ACHE | |
| SCHEMBL4751839 | 0.91 | KIF11 (0.34) | SLC6A1SCN9AKIF11ALDH1A1ACHE | |
| SCHEMBL4749135 | 0.88 | SLC6A5 (0.32) | MEN1KMT2ASCN9AKIF11ACHE | |
| SCHEMBL4019044 | 0.87 | BCHE (0.34) | MEN1KMT2ASCN9AACHE | |
| SCHEMBL4752003 | 0.87 | BCHE (0.34) | MEN1KMT2ASCN9AACHE | |
| SCHEMBL4752006 | 0.87 | BCHE (0.34) | MEN1KMT2ASCN9AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |