Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | DYRK2 | Q92630 | 5/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749098 | 1.00 | KMT2A (0.55) | KMT2AMAPTKDM4EALDH1A1DYRK2 | |
| SCHEMBL19721154 | 0.77 | MAPT (0.50) | KMT2AMAPTKDM4EALDH1A1DYRK2 | |
| SCHEMBL3885765 | 0.76 | MEN1 (0.61) | KMT2AMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL3885759 | 0.76 | MEN1 (0.61) | KMT2AMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL3887396 | 0.75 | KMT2A (0.60) | KMT2AMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL3887393 | 0.75 | KMT2A (0.60) | KMT2AMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL418900 | 0.74 | MAPT (0.55) | KMT2AMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL448179 | 0.74 | MAPT (0.55) | KMT2AMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL14041425 | 0.73 | KMT2A (0.60) | KMT2AMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4748813 | 0.73 | KMT2A (0.60) | KMT2AMAPTKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121861-A2 | PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-09 | — | — | WO | disclosed |