Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 9/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749137 | 1.00 | ACHE (0.35) | ACHEHTR7KIF11KDRBCHE | |
| SCHEMBL4749505 | 0.98 | KIF11 (0.35) | ACHEHTR7KIF11KDRBCHE | |
| SCHEMBL4752741 | 0.98 | KIF11 (0.35) | ACHEHTR7KIF11KDRBCHE | |
| SCHEMBL4752081 | 0.98 | KIF11 (0.35) | ACHEHTR7KIF11KDRBCHE | |
| SCHEMBL4751358 | 0.98 | KIF11 (0.35) | ACHEHTR7KIF11KDRBCHE | |
| SCHEMBL4751736 | 0.98 | KIF11 (0.35) | ACHEHTR7KIF11KDRBCHE | |
| SCHEMBL4751967 | 0.97 | HTR7 (0.35) | ACHEHTR7KIF11KDRBCHE | |
| SCHEMBL4751963 | 0.97 | HTR7 (0.35) | ACHEHTR7KIF11KDRBCHE | |
| SCHEMBL4019102 | 0.97 | ACHE (0.37) | ACHEHTR7KIF11KDRBCHE | |
| SCHEMBL4025347 | 0.95 | KIF11 (0.37) | ACHEHTR7KIF11KDRBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |