Biphenyl

Biphenyl

SCHEMBL4749209

Oc1ccccc1-c1ccccc1OP(O)Cl.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.47
ALDH1A1 P00352 1/20 0.47
BCL2L1 Q07817 1/20 0.47
HSD17B10 Q99714 1/20 0.47
FABP7 O15540 1/20 0.38
FABP3 P05413 1/20 0.38
FABP5 Q01469 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
BACE1 P56817 1/20 0.35
CASP3 P42574 2/20 0.35
SENP8 Q96LD8 2/20 0.35
SENP7 Q9BQF6 2/20 0.35
SENP6 Q9GZR1 2/20 0.35
ALOX15 P16050 2/20 0.35
ADORA2A P29274 2/20 0.35
TSHR P16473 2/20 0.35
CHUK O15111 1/20 0.35
TXNRD1 Q16881 1/20 0.35
NOX4 Q9NPH5 1/20 0.35
ADORA3 P0DMS8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7603952 0.93 ALDH1A1 (0.39) HPGDALDH1A1BCL2L1HSD17B10FABP7
SCHEMBL339290 0.84 CA1 (0.31) TSHRCA1CA2TP53NCOA1
Biphenyl SCHEMBL4749212 0.82 HPGD (0.62) HPGDALDH1A1BCL2L1HSD17B10L3MBTL1
SCHEMBL31604211 0.78 ALDH1A1 (0.41) HPGDALDH1A1BCL2L1HSD17B10FABP7
SCHEMBL10937183 0.78 CA2 (0.48) HPGDALDH1A1HSD17B10L3MBTL1ALOX15
SCHEMBL3962595 0.75 HPGD (0.39) HPGDALDH1A1BCL2L1HSD17B10FABP7
SCHEMBL6974 0.73 CA1 (0.35) HPGDALDH1A1L3MBTL1TSHRSMN1; SMN2
SCHEMBL7603958 0.73 ALDH1A1 (0.52) HPGDALDH1A1BCL2L1HSD17B10L3MBTL1
SCHEMBL13080138 0.72 MAPK1 (0.44) HPGDALDH1A1BCL2L1HSD17B10FABP7
SCHEMBL31255937 0.71 ALDH1A1 (0.55) HPGDALDH1A1BCL2L1HSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008124468-A1 A CALIXARENE BISPHOSPHITE LIGAND FOR USE IN HYDROFORMYLATION PROCESSES DOW GLOBAL TECHNOLOGIES INC. (US) 2008-10-16 WO disclosed