Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL4749209 | 0.93 | HPGD (0.47) | ALDH1A1HPGDHSD17B10BCL2L1FABP7 | |
| SCHEMBL339290 | 0.90 | CA1 (0.31) | CA2TP53CA1TSHRCA4 | |
| SCHEMBL31604211 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10BCL2L1FABP7 | |
| SCHEMBL10937183 | 0.84 | CA2 (0.48) | ALDH1A1HPGDHSD17B10CA2TP53 | |
| SCHEMBL6974 | 0.79 | CA1 (0.35) | ALDH1A1HPGDCA2TP53CA1 | |
| SCHEMBL7603958 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10BCL2L1CA2 | |
| SCHEMBL3962595 | 0.77 | HPGD (0.39) | ALDH1A1HPGDHSD17B10BCL2L1FABP7 | |
| SCHEMBL31255937 | 0.76 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10BCL2L1CA2 | |
| SCHEMBL4586197 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10BCL2L1FABP7 | |
| SCHEMBL28682908 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10BCL2L1FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477998-B1 | ORGANOPHOSPHORUS COMPOUNDS, CATALYTIC SYSTEMS INCLUDING SAID COMPOUNDS, AND HYDROCYANATION METHOD USING SAID CATALYTIC SYSTEMS | RHODIA OPERATIONS (FR) | 2014-02-26 | — | — | EP | disclosed |
| EP-2477998-A1 | ORGANOPHOSPHORUS COMPOUNDS, CATALYTIC SYSTEMS INCLUDING SAID COMPOUNDS, AND HYDROCYANATION METHOD USING SAID CATALYTIC SYSTEMS | Rhodia Opérations (FR) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011032835-A1 | ORGANOPHOSPHORUS COMPOUNDS, CATALYTIC SYSTEMS INCLUDING SAID COMPOUNDS, AND HYDROCYANATION METHOD USING SAID CATALYTIC SYSTEMS | RHODIA OPERATIONS (FR) | 2011-03-24 | — | — | WO | disclosed |
| US-6437192-B1 | FERROCENE-BASED LIGANDS AND GROUP VIII METAL OR COMPOUND (SUCH AS RHODIUM) AS CATALYSTS; LOW COST | E. I. DU PONT DE NMEOURS AND COMPANY | 2002-08-20 | — | — | US | disclosed |