Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970899 | 0.75 | ACHE (0.62) | MEN1KMT2AHTR2A | |
| SCHEMBL10379361 | 0.74 | GRIA4 (0.46) | MEN1KMT2AMITFADRB2 | |
| Hydrochloric Acid SCHEMBL18587402 | 0.74 | ACHE (0.61) | MEN1KMT2AHTR2A | |
| Water SCHEMBL22683358 | 0.74 | ACHE (0.61) | MEN1KMT2AADRB2DRD3HTR2A | |
| SCHEMBL8552701 | 0.73 | CYP3A4 (0.67) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL12228088 | 0.73 | ADRB2 (0.44) | MEN1KMT2AMITFADRB2ADRB1 | |
| SCHEMBL22475158 | 0.73 | MEN1 (0.50) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL10378492 | 0.72 | GRIA4 (0.44) | MEN1KMT2A | |
| SCHEMBL21733038 | 0.71 | CACNA2D1 (0.46) | MEN1KMT2A | |
| SCHEMBL10378535 | 0.71 | GRIA4 (0.43) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141057-A1 | DEUTERATED PIMAVANSERIN 1- (4-FLU0R0BENZYL) -3- (4-ISOBUTOXYBENZYL) -1- ( L-METHYL-PIPERIDIN-4-YL) -UREA | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-11-20 | — | — | WO | disclosed |