Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20745110 | 0.83 | LIPC (0.34) | EPHX2LIPG | |
| SCHEMBL600619 | 0.82 | CHRM2 (0.32) | GAA | |
| SCHEMBL600575 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL27888454 | 0.81 | EPHX2 (0.46) | EPHX2LIPGALDH1A1TSHRNPC1 | |
| SCHEMBL3010206 | 0.80 | KMT2A (0.34) | — | |
| SCHEMBL1574372 | 0.78 | CRBN (0.36) | EPHX2LIPGTSHRNPC1 | |
| SCHEMBL27536365 | 0.77 | EPHX2 (0.41) | EPHX2LIPGALDH1A1TSHRNPC1 | |
| SCHEMBL9405869 | 0.77 | EPHX2 (0.40) | EPHX2ALDH1A1TSHRHPGD | |
| SCHEMBL21047710 | 0.76 | GBA1 (0.40) | EPHX2ALDH1A1TSHRHPGD | |
| SCHEMBL21047634 | 0.76 | GBA1 (0.40) | EPHX2ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119721-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119721-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |