Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759838 | 0.90 | CYP19A1 (0.33) | ALDH1A1 | |
| SCHEMBL17492928 | 0.89 | ALDH1A1 (0.30) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL19339209 | 0.89 | ALDH1A1 (0.30) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL17459638 | 0.89 | ALDH1A1 (0.30) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL17459582 | 0.89 | ALDH1A1 (0.30) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL19309747 | 0.86 | TRIM24 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3980699 | 0.86 | — | — | |
| SCHEMBL600619 | 0.82 | CHRM2 (0.32) | CHRM4CHRM5CHRM1 | |
| SCHEMBL4749367 | 0.81 | EPHX2 (0.40) | ALDH1A1 | |
| SCHEMBL184319 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119524839-A | Catalyst for selectively catalyzing hydrogenation of phenol compounds and preparation method thereof | 嘉庚创新实验室 | 2025-02-28 | — | — | CN | claimed |
| EP-4212523-B1 | PYRAZOLE AMIDE COMPOUNDS AS IRAK INHIBITORS | RIGEL PHARMACEUTICALS INC (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-4650351-A1 | INHIBITOR OF COMPLEMENT FACTOR B | Nanjing Chia Tai Tianqing Pharmaceutical Co., Ltd. (CN) | 2025-11-19 | — | — | EP | disclosed |
| US-20250333408-A1 | PYRIMID-2-YL-PYRAZOLE COMPOUNDS AS IRAK INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2025-10-30 | — | — | US | disclosed |
| US-12384775-B2 | Pyrimid-2-yl-pyrazole compounds as IRAK inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2025-08-12 | — | — | US | disclosed |
| CN-119524839-A | Catalyst for selectively catalyzing hydrogenation of phenol compounds and preparation method thereof | 嘉庚创新实验室 | 2025-02-28 | — | — | CN | disclosed |
| EP-4496794-A1 | PYRIMID-2-YL-PYRAZOLE COMPOUNDS AS IRAK INHIBITORS | Rigel Pharmaceuticals, Inc. (US) | 2025-01-29 | — | — | EP | disclosed |
| WO-2024149261-A1 | INHIBITOR OF COMPLEMENT FACTOR B | 南京正大天晴制药有限公司 | 2024-07-18 | — | — | WO | disclosed |
| US-11993594-B2 | IRAK inhibitors and method for making and using | RIGEL PHARMACEUTICALS, INC. (US) | 2024-05-28 | — | — | US | disclosed |
| US-11939317-B2 | Amide compounds and method for making and using | RIGEL PHARMACEUTICALS, INC. (US) | 2024-03-26 | — | — | US | disclosed |
| WO-2007107566-A1 | BENZIMIDAZOLES WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-09-27 | — | — | WO | disclosed |
| US-20070043219-A1 | 4-Alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-7148377-B2 | 4-Alkoxy cyclohexane-1-amino-carboxylic acid esters and method for the production thereof | BAYER CROPSCIENCE AG (DE) | 2006-12-12 | — | — | US | disclosed |
| US-20040039223-A1 | 4-Alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-02-26 | — | — | US | disclosed |
| EP-1309562-A1 | 4-ALKOXY CYCLOHEXANE-1 AMINO CARBOXYLIC ACID ESTERS AND METHOD FOR THE PRODUCTION THEREOF | Bayer CropScience AG (DE) | 2003-05-14 | — | — | EP | disclosed |
| EP-1082449-B1 | METHOD FOR STEREOSELECTIVE PRODUCTION OF SUBSTITUTED CYCLOHEXYLCYANHYDRINS | BAYER CROPSCIENCE AG (DE) | 2003-03-05 | — | — | EP | disclosed |
| US-6465222-B1 | REACTING 4-SUBSTITUTED CYCLOHEXANONE WITH CYANIDE IN PRESENCE OF OXYNITRILASE; CYANATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-15 | — | — | US | disclosed |
| WO-2002002532-A1 | 4-ALKOXY CYCLOHEXANE-1 AMINO CARBOXYLIC ACID ESTERS AND METHOD FOR THE PRODUCTION THEREOF | BAYER CROPSCIENCE AG (DE) | 2002-01-10 | — | — | WO | disclosed |
| US-5654483-A | REACTING ALKOXY-SUBSTITUTED CYCLOHEXANONE WITH DIPHENYLAMINE WHILE FORMING CYCLOHEXANONE FROM ALKOXY-SUBSTITUTED PHENOL IN PRESENCE OF SURFACE-SUPPORTED HYDROGEN TRANSFER CATALYST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-08-05 | — | — | US | disclosed |
| WO-1993007119-A1 | NOVEL ANTIMALARIAL PEROXIDES AND PROCESSES FOR THEIR PRODUCTION AND USE | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1993-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12384775-B2 | Pyrimid-2-yl-pyrazole compounds as IRAK inhibitors | IRAK2, IRAK3, IRAK1 | ALDH1A1 1493/4885SMN1; SMN2 1685/4885CYP1A2 3679/4885 |
| US-20250333408-A1 | PYRIMID-2-YL-PYRAZOLE COMPOUNDS AS IRAK INHIBITORS | IRAK2, IRAK3, IRAK1 | ALDH1A1 1493/4885SMN1; SMN2 1685/4885CYP1A2 3679/4885 |
| US-20070043219-A1 | 4-Alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | ALDH7A1, DDC, ABAT | ALDH1A1 143/4885SMN1; SMN2 3941/4885CYP1A2 48/4885 |
| US-11939317-B2 | Amide compounds and method for making and using | IRAK1, IRAK2, IRAK3 | ALDH1A1 1076/4885SMN1; SMN2 1697/4885CYP1A2 3695/4885 |
| US-11993594-B2 | IRAK inhibitors and method for making and using | IRAK1, IRAK2, IRAK3 | ALDH1A1 1451/4885SMN1; SMN2 1182/4885CYP1A2 4308/4885 |
| US-20040039223-A1 | 4-Alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | ALDH7A1, CYP51A1, ABAT | ALDH1A1 144/4885SMN1; SMN2 3599/4885CYP1A2 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.