Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 6/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749489 | 1.00 | KIF11 (0.36) | KIF11ESR1HTR7BCHEKDM4E | |
| SCHEMBL4749343 | 0.95 | KIF11 (0.35) | KIF11HTR7BCHEKDM4EALDH1A1 | |
| SCHEMBL4749341 | 0.95 | KIF11 (0.35) | KIF11HTR7BCHEKDM4EALDH1A1 | |
| SCHEMBL4025347 | 0.93 | KIF11 (0.37) | KIF11HTR7BCHEKDM4EALDH1A1 | |
| SCHEMBL4749456 | 0.92 | KIF11 (0.39) | KIF11HTR7BCHEKDM4EALDH1A1 | |
| SCHEMBL4749461 | 0.92 | KIF11 (0.39) | KIF11HTR7BCHEKDM4EALDH1A1 | |
| SCHEMBL4023151 | 0.92 | HTR7 (0.37) | KIF11HTR7BCHEKDM4EALDH1A1 | |
| SCHEMBL4019102 | 0.92 | ACHE (0.37) | KIF11HTR7BCHEKDM4EALDH1A1 | |
| SCHEMBL4752081 | 0.91 | KIF11 (0.35) | KIF11HTR7BCHEKDM4EALDH1A1 | |
| SCHEMBL4751736 | 0.91 | KIF11 (0.35) | KIF11HTR7BCHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |