Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749278 | 0.88 | NPC1 (0.55) | NPC1RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL4752214 | 0.87 | L3MBTL1 (0.66) | NPC1RAB9AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4749629 | 0.82 | NPC1 (0.61) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL4751468 | 0.81 | MAPK8 (0.64) | RAB9AALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL4737934 | 0.81 | L3MBTL1 (0.76) | RAB9AKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL23413572 | 0.78 | NPC1 (0.76) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL4752212 | 0.77 | NPC1 (0.67) | NPC1RAB9AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL5061069 | 0.77 | RAB9A (0.86) | NPC1RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL4751921 | 0.76 | L3MBTL1 (0.54) | NPC1RAB9AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4751453 | 0.76 | L3MBTL1 (0.64) | NPC1RAB9AKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | disclosed |