Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16246579 | 0.84 | CA1 (0.42) | PARP1ALOX15SMN1; SMN2PDPK1CA12 | |
| SCHEMBL11222595 | 0.82 | PARP1 (0.37) | PARP1ALOX15SMN1; SMN2PDPK1CA12 | |
| SCHEMBL27645647 | 0.80 | POLB (0.49) | PARP1ALOX15SMN1; SMN2PDPK1CA12 | |
| SCHEMBL338619 | 0.75 | CYP2C19 (0.36) | PARP1CYP1A2HSD17B10CYP2C19FEN1 | |
| SCHEMBL9718690 | 0.74 | MAPK14 (0.38) | PARP1ALOX15SMN1; SMN2PDPK1CA12 | |
| SCHEMBL28233407 | 0.73 | PARP1 (0.51) | PARP1TTRL3MBTL1COMTMEN1 | |
| Benzimidazole SCHEMBL1801413 | 0.73 | PARP1 (0.42) | PARP1ALOX15SMN1; SMN2PDPK1CA12 | |
| SCHEMBL1019602 | 0.72 | QPCT (0.42) | PARP1ALOX15SMN1; SMN2PDPK1CA12 | |
| SCHEMBL11222589 | 0.71 | PARP1 (0.50) | PARP1TTRCOMTMEN1POLB | |
| SCHEMBL7196214 | 0.71 | L3MBTL1 (0.57) | TTRHSD17B10L3MBTL1MYCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124524-A2 | ARYL SULFONAMIDE COMPOUNDS AS MODULATORS OF THE CCK2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-16 | — | — | WO | claimed |
| US-20250099345-A1 | UV FILTER COMPOSITIONS COMPRISING CLOSED-CELL METAL OXIDE PARTICLES | BASF SE (DE) | 2025-03-27 | — | — | US | disclosed |
| CN-110540523-B | Method for preparing sulfo-substituted benzimidazole and derivative thereof | 安徽圣诺贝化学科技有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-110540523-A | Method for preparing sulfo-substituted benzimidazole and derivative thereof | ANHUI SHENGNUOBEI CHEMICAL TECH CO LTD | 2019-12-06 | — | — | CN | disclosed |
| CN-108348421-A | Personal care compositions containing cyclic carboxylic acids | 荷兰联合利华有限公司 | 2018-07-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250099345-A1 | UV FILTER COMPOSITIONS COMPRISING CLOSED-CELL METAL OXIDE PARTICLES | SUN2, ERCC4, XPA | PARP1 2690/4885ALOX15 1326/4885SMN1; SMN2 3224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.