Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | NT5C2 | P49902 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22468121 | 0.80 | MAPK14 (0.35) | MAPK14HDAC6SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL9718685 | 0.78 | DPP4 (0.43) | MAPK14HDAC6KDM4EALDH1A1HPGD | |
| SCHEMBL3860255 | 0.76 | ADORA3 (0.46) | SMN1; SMN2RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL28343825 | 0.74 | HDAC6 (0.39) | HDAC6KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL4749862 | 0.74 | PARP1 (0.39) | MAPK14SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL22468120 | 0.69 | ALDH1A1 (0.36) | MAPK14HDAC6SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL28147663 | 0.68 | TSHR (0.40) | HDAC6SMN1; SMN2ALDH1A1HPGDHTT | |
| SCHEMBL20569781 | 0.68 | PTGS2 (0.39) | SMN1; SMN2ALDH1A1RCE1TSHR | |
| SCHEMBL6389553 | 0.68 | TYMP (0.46) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL22444090 | 0.67 | MYC (0.40) | SMN1; SMN2KDM4EALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144081-A | Sunscreen agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |