Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4284056 | 1.00 | HTR7 (0.48) | HTR7HSD17B10MAPK1LMNARAB9A | |
| SCHEMBL4287898 | 0.90 | SLC6A2 (0.44) | LMNARAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL4282105 | 0.87 | POLB (0.48) | LMNARAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL4294740 | 0.83 | MAN1B1 (0.43) | CCR3POLB | |
| SCHEMBL4287630 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4284770 | 0.82 | ALDH1A1 (0.41) | RAB9AALDH1A1KMT2ACCR3POLB | |
| SCHEMBL4291132 | 0.80 | MAPT (0.42) | RAB9AKMT2AMEN1SMN1; SMN2CCR3 | |
| SCHEMBL4973478 | 0.79 | ADRB1 (0.40) | RAB9AALDH1A1SMN1; SMN2CCR3POLB | |
| SCHEMBL4284858 | 0.78 | CA1 (0.42) | LMNARAB9AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8116637 | 0.78 | CCR3 (0.44) | RAB9ASMN1; SMN2CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |