Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | PARG | Q86W56 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4291309 | 0.79 | LMNA (0.36) | LMNAMAPTHTR7 | |
| SCHEMBL3648904 | 0.75 | LMNA (0.48) | LMNAMAPTHTR7PARG | |
| SCHEMBL1492377 | 0.72 | LMNA (0.44) | LMNAMAPTHTR7PARG | |
| SCHEMBL20371571 | 0.69 | LMNA (0.46) | LMNAMAPTHPGDPARG | |
| SCHEMBL4295055 | 0.69 | LMNA (0.35) | LMNAMAPTHTR7 | |
| SCHEMBL8129587 | 0.68 | LMNA (0.54) | LMNAMAPTHTR6KDM4E | |
| SCHEMBL14487357 | 0.66 | APEX1 (0.56) | LMNAMAPTKDM4EHPGD | |
| SCHEMBL9292292 | 0.65 | ACHE (0.48) | LMNALTA4H | |
| SCHEMBL15730254 | 0.65 | LMNA (0.49) | LMNAMAPTKDM4EHPGD | |
| SCHEMBL7051699 | 0.63 | NPY1R (0.48) | HPGDLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |