Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15255524 | 1.00 | ALDH1A1 (0.34) | ALDH1A1LMNAHTTHCRTR1HCRTR2 | |
| SCHEMBL15255528 | 1.00 | ALDH1A1 (0.34) | ALDH1A1LMNAHTTHCRTR1HCRTR2 | |
| SCHEMBL10102236 | 0.90 | NR3C1 (0.32) | — | |
| SCHEMBL10102232 | 0.90 | NR3C1 (0.32) | — | |
| SCHEMBL15255529 | 0.82 | S1PR1 (0.43) | ALDH1A1LMNAHTT | |
| SCHEMBL4788079 | 0.82 | S1PR1 (0.43) | ALDH1A1LMNAHTT | |
| SCHEMBL15255527 | 0.82 | S1PR1 (0.43) | ALDH1A1LMNAHTT | |
| SCHEMBL10101781 | 0.75 | POLB (0.34) | — | |
| SCHEMBL10101780 | 0.75 | POLB (0.34) | — | |
| SCHEMBL10101782 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536157-B2 | Non-steroidal compounds | THE UNIVERSITY OF MELBOURNE (AU) | 2013-09-17 | — | — | US | disclosed |
| WO-2008124878-A1 | NON-STEROIDAL COMPOUNDS | CRYPTOPHARMA PTY LTD (AU) | 2008-10-23 | — | — | WO | disclosed |