Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552402 | 1.00 | MAPT (0.35) | MAPTKDM4ECRHBPCRHR2POLB | |
| SCHEMBL4622980 | 0.93 | KDM4E (0.32) | MAPTKDM4ECRHBPCRHR2 | |
| SCHEMBL6757630 | 0.81 | HSD17B10 (0.38) | — | |
| SCHEMBL6003462 | 0.81 | MAPT (0.42) | MAPTKDM4ECRHBPCRHR2POLB | |
| SCHEMBL722867 | 0.81 | MAPT (0.42) | MAPTKDM4ECRHBPCRHR2POLB | |
| Hydrochloric Acid SCHEMBL6756049 | 0.79 | HSD17B10 (0.37) | — | |
| SCHEMBL4624017 | 0.78 | ALOX5AP (0.36) | MAPTKDM4ECRHBPCRHR2POLB | |
| SCHEMBL5404508 | 0.76 | MAPT (0.39) | MAPTKDM4ECRHBPCRHR2POLB | |
| SCHEMBL7875124 | 0.76 | MAPT (0.39) | MAPTKDM4ECRHBPCRHR2POLB | |
| SCHEMBL30688717 | 0.76 | MAPT (0.39) | MAPTKDM4ECRHBPCRHR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905169-B1 | Precursors of polybenzoxazoles and polybenzothiazoles | INFINEON TECHNOLOGIES AG (DE) | 2008-04-02 | — | — | EP | disclosed |
| EP-0906903-B1 | Bis-o-amino(thio)phenols and their preparartion | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6150558-A | Bis-o-amino(thio)phenols, and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-11-21 | — | — | US | disclosed |
| EP-0906903-A2 | Bis-o-amino(thio)phenols and their preparartion | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-04-07 | — | — | EP | disclosed |
| EP-0905169-A2 | Precursors of polybenzoxazoles and polybenzothiazoles | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | disclosed |