Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747714 | 0.74 | MAPK1 (0.39) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL11486011 | 0.70 | PNMT (0.49) | PNMT | |
| SCHEMBL4072415 | 0.69 | KDM4E (0.42) | KDM4EALDH1A1KMT2AMAPTNPSR1 | |
| SCHEMBL6369738 | 0.69 | TMEM97 (0.57) | PNMTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4064222 | 0.68 | GRM5 (0.45) | KDM4EALDH1A1HPGDKMT2ANPSR1 | |
| SCHEMBL6369527 | 0.67 | HTR2C (0.50) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6369549 | 0.66 | PNMT (0.55) | PNMTKMT2A | |
| SCHEMBL153999 | 0.66 | MAOA (0.57) | KDM4EALDH1A1 | |
| SCHEMBL31841937 | 0.66 | MAOA (0.57) | KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11491868 | 0.65 | PNMT (0.47) | PNMTCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123755-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTAM TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |