Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6337523 | 0.82 | HDAC8 (0.39) | HDAC8ALDH1A1SMN1; SMN2MAPTMGAM | |
| SCHEMBL971386 | 0.82 | SCN4A (0.40) | HDAC8ALDH1A1SMN1; SMN2MAPTMGAM | |
| SCHEMBL27769472 | 0.78 | L3MBTL1 (0.44) | HDAC8ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL6027073 | 0.75 | KMT2A (0.43) | ALDH1A1SMN1; SMN2HSD17B10KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL9124572 | 0.74 | NOS1 (0.40) | HDAC8MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL25296039 | 0.74 | HDAC8 (0.47) | HDAC8ALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL6891951 | 0.74 | MEN1 (0.43) | ALDH1A1MAPTHPGDKDM4ERAB9A | |
| SCHEMBL27843276 | 0.73 | KDM4E (0.38) | HDAC8ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL2066826 | 0.72 | KDM4E (0.46) | ALDH1A1SMN1; SMN2MAPTHPGDALOX15 | |
| SCHEMBL1774699 | 0.72 | KDM4E (0.44) | HDAC8ALDH1A1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113439084-B | Sesqui-carcinomycin analogue | 奥克兰联合服务有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-116265458-A | Benzothiophene derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-06-20 | — | — | CN | disclosed |
| EP-3917933-A1 | DUOCARMYCIN ANALOGUES | Auckland Uniservices Limited (NZ) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020157662-A1 | DUOCARMYCIN ANALOGUES | AUCKLAND UNISERVICES LIMITED (NZ) | 2020-08-06 | — | — | WO | disclosed |
| CN-106170486-B | Novel indazolecarboxamides, method for the production thereof, pharmaceutical preparations containing the same and use thereof for producing medicaments | 拜耳医药股份有限公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-105669668-A | Pyridoindazole or benzopyridoindazole derivatives and synthesis method thereof | 上海大学 | 2016-06-15 | — | — | CN | disclosed |
| CN-101880280-B | Bicyclic pyrimidinones and uses thereof | SHANGHAI INST ORGANIC CHEM | 2014-07-16 | — | — | CN | disclosed |
| CN-101627019-B | Bicyclic pyrimidinones and uses thereof | AVEXA LTD | 2013-07-10 | — | — | CN | disclosed |
| EP-2411001-A1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | Merck Sharp & Dohme Corp. (US) | 2012-02-01 | — | — | EP | disclosed |
| US-8048537-B2 | Cyclometalated transition metal complex and organic light emitting device using the same | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2011-11-01 | — | — | US | disclosed |
| WO-2006047277-A2 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-04 | — | — | WO | disclosed |
| CN-1753671-A | 1,3-substitued cycloalkyl derivatives having acidic, mostly heterocyclic groups, processes for their preparation and their use as pharmaceuticals | SANNOFFE AVENTIS PHARMA GMBH (DE) | 2006-03-29 | — | — | CN | disclosed |
| EP-1381366-A4 | INDOLE, AZAINDOLE AND RELATED HETEROCYCLIC AMIDOPIPERAZINE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2005-02-16 | — | — | EP | disclosed |
| US-6825201-B2 | ANTIVIRAL ACTIVITY; TREATMENT OF HIV AND AIDS | BRISTOL-MYERS SQUIBB COMPANY | 2004-11-30 | — | — | US | disclosed |
| CN-1520295-A | Indole, azaindole and related heterocyclic amidopiperazine derivatives | ����˹�ж�-����˹˹������˾ | 2004-08-11 | — | — | CN | disclosed |
| EP-1381366-A2 | INDOLE, AZAINDOLE AND RELATED HETEROCYCLIC AMIDOPIPERAZINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-01-21 | — | — | EP | disclosed |
| US-20030096825-A1 | Indole, azaindole and related heterocyclic amidopiperazine derivatives | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2003-05-22 | — | — | US | disclosed |
| EP-1268486-A2 | FUSED HETEROCYCLIC DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2003-01-02 | — | — | EP | disclosed |
| WO-2002085301-A2 | INDOLE, AZAINDOLE AND RELATED HETEROCYCLIC AMIDOPIPERAZINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-10-31 | — | — | WO | disclosed |
| WO-2001074823-A2 | FUSED HETEROCYCLIC DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096825-A1 | Indole, azaindole and related heterocyclic amidopiperazine derivatives | IDO1, IDO2, INMT | HDAC8 1007/4885ALDH1A1 3050/4885SMN1; SMN2 4791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.