Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746893 | 0.89 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL4750426 | 0.89 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL4749742 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KDM4ERAB9AMAPTHPGD | |
| SCHEMBL5761600 | 0.77 | PARP1 (0.43) | — | |
| SCHEMBL4751796 | 0.77 | KCNH2 (0.47) | L3MBTL1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4834468 | 0.77 | KCNH2 (0.47) | L3MBTL1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL14157834 | 0.77 | KCNH2 (0.47) | L3MBTL1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4838068 | 0.77 | KCNH2 (0.47) | L3MBTL1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL5764199 | 0.76 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL8823728 | 0.76 | DRD2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130319-A2 | NOVEL N-TETRAHYDRONAPHTALENE OR N-CHROMANE CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | disclosed |