Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17133607 | 0.84 | AHR (0.56) | SMN1; SMN2MAPTAHRKDM4EALDH1A1 | |
| SCHEMBL27883 | 0.75 | CA12 (0.65) | SMN1; SMN2MAPTAHRKDM4EALDH1A1 | |
| SCHEMBL14880493 | 0.74 | AHR (0.57) | SMN1; SMN2MAPTAHRKDM4EALDH1A1 | |
| SCHEMBL1645118 | 0.71 | CHRNA7 (0.55) | SMN1; SMN2MAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL10411682 | 0.71 | ALDH1A1 (0.72) | SMN1; SMN2MAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL7958651 | 0.70 | NFE2L2 (0.56) | SMN1; SMN2MAPTAHRKDM4EALDH1A1 | |
| SCHEMBL6752282 | 0.69 | KDM4E (0.73) | SMN1; SMN2MAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL29016917 | 0.69 | AHR (0.72) | AHRKDM4EALDH1A1CYP2A6CYP3A4 | |
| SCHEMBL24897242 | 0.68 | CYP1A2 (0.64) | SMN1; SMN2MAPTAHRKDM4EALDH1A1 | |
| SCHEMBL11090821 | 0.68 | CYP1A2 (0.77) | SMN1; SMN2MAPTKDM4EALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121387-A1 | SUBSTITUTED TRIAZINE COMPOUNDS FOR NERVE REGENERATION | UNIVERSITY OF MIAMI (US) | 2008-10-09 | — | — | WO | disclosed |