SCHEMBL4750622

SCHEMBL4750622

c1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4nc5c6ccccc6c6ccccc6c5nc4-c4ccc(N(c5ccccc5)c5ccc(-c6ccccc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADK P55263 1/20 0.40
KDM4E B2RXH2 4/20 0.38
TDP1 Q9NUW8 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
ALDH1A1 P00352 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
DHODH Q02127 3/20 0.38
GAA P10253 3/20 0.37
HTT P42858 2/20 0.37
HPGD P15428 2/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11947003 0.96 ALDH1A1 (0.41) ADKKDM4ETDP1L3MBTL1ALDH1A1
SCHEMBL16543285 0.87 KDM4E (0.45) KDM4ETDP1L3MBTL1ALDH1A1MAPT
SCHEMBL14211983 0.87 KDM4E (0.45) KDM4ETDP1L3MBTL1ALDH1A1MAPT
SCHEMBL11947021 0.86 ADORA2A (0.39) ADKKDM4ETDP1L3MBTL1ALDH1A1
SCHEMBL19932430 0.85 GAA (0.41) KDM4EALDH1A1CYP1A2MAPTCYP2C19
SCHEMBL14447265 0.85 ALDH1A1 (0.46) ADKKDM4ETDP1L3MBTL1ALDH1A1
SCHEMBL17879133 0.85 TDP1 (0.46) ADKKDM4ETDP1L3MBTL1ALDH1A1
SCHEMBL14447271 0.85 ALDH1A1 (0.46) ADKKDM4ETDP1L3MBTL1ALDH1A1
SCHEMBL13492528 0.85 ALDH1A1 (0.37) ADKKDM4ETDP1L3MBTL1ALDH1A1
SCHEMBL14447304 0.83 ALDH1A1 (0.48) ADKKDM4ETDP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623523-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-07 US disclosed
US-8623523-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-07 US disclosed
US-20120211738-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-08-23 US disclosed
US-20120211738-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-08-23 US disclosed
US-8173277-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-08 US disclosed
US-8173277-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-08 US disclosed
US-20110186825-A1 Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-08-04 US disclosed
US-20110186825-A1 Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-08-04 US disclosed
US-7901792-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-03-08 US disclosed
US-7901792-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-03-08 US disclosed
WO-2007032258-A1 QUINOXALINE DERIVATIVE, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC APPLIANCE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-03-22 WO disclosed
US-20070059553-A1 Quinoxaline derivative, and light emitting element, light emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-03-15 US disclosed
US-20070059553-A1 Quinoxaline derivative, and light emitting element, light emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070059553-A1 Quinoxaline derivative, and light emitting element, light emitting device, and electronic appliance using the same CRY1, CRY2, ARL1 ADK 2480/4885KDM4E 347/4885TDP1 2672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.