Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754100 | 0.90 | TP53 (0.53) | TP53KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4267618 | 0.80 | TP53 (0.56) | TP53KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4789503 | 0.80 | TP53 (0.49) | TP53KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4750935 | 0.77 | TP53 (0.48) | TP53KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4753094 | 0.72 | GNRHR (0.41) | KMT2AMEN1MAPTCYP3A4NPSR1 | |
| SCHEMBL4091501 | 0.72 | TP53 (0.45) | TP53KMT2AMAPTTAAR1POLB | |
| SCHEMBL4091503 | 0.72 | TP53 (0.45) | TP53KMT2AMAPTTAAR1POLB | |
| SCHEMBL13742387 | 0.72 | TP53 (0.46) | TP53MAPTTAAR1POLBTHRB | |
| SCHEMBL4105415 | 0.71 | TP53 (0.46) | TP53KMT2AMAPTTAAR1POLB | |
| SCHEMBL4752600 | 0.71 | KIF11 (0.42) | KMT2AMEN1ALDH1A1CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147852-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-12-04 | — | — | WO | disclosed |