Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101940 | 0.83 | KIF11 (0.45) | KIF11TLR7CYP3A4SCN9ASCN10A | |
| SCHEMBL4752599 | 0.81 | KIF11 (0.46) | KIF11TLR7CYP3A4SCN9ASCN10A | |
| SCHEMBL4753094 | 0.79 | GNRHR (0.41) | KIF11TLR7CYP3A4SCN9ASCN10A | |
| SCHEMBL4753082 | 0.79 | TLR7 (0.41) | KIF11TLR7CYP3A4SCN9ASCN10A | |
| SCHEMBL5248653 | 0.79 | KIF11 (0.42) | KIF11TLR7CYP3A4 | |
| SCHEMBL4754113 | 0.78 | PDE4A (0.43) | TLR7ALDH1A1HPGDSMN1; SMN2PDE4A | |
| SCHEMBL4101670 | 0.78 | PDE4A (0.46) | TLR7ALDH1A1HPGDSMN1; SMN2PDE4A | |
| SCHEMBL5250052 | 0.76 | KIF11 (0.40) | KIF11TLR7SMN1; SMN2 | |
| SCHEMBL5325935 | 0.75 | KIF11 (0.39) | KIF11TLR7L3MBTL1 | |
| SCHEMBL5754463 | 0.69 | SYK (0.43) | KIF11CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147852-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-12-04 | — | — | WO | disclosed |