Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 6/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753082 | 0.85 | TLR7 (0.41) | GNRHRKIF11BRD4TLR7CYP3A4 | |
| SCHEMBL4102093 | 0.81 | KIF11 (0.46) | GNRHRKIF11BRD4TLR7CYP3A4 | |
| SCHEMBL5248653 | 0.80 | KIF11 (0.42) | GNRHRKIF11BRD4TLR7CYP3A4 | |
| SCHEMBL5250052 | 0.80 | KIF11 (0.40) | GNRHRKIF11BRD4TLR7MAPT | |
| SCHEMBL5754463 | 0.80 | SYK (0.43) | KIF11BRD4CYP3A4MAPT | |
| SCHEMBL4752600 | 0.79 | KIF11 (0.42) | KIF11TLR7CYP3A4SCN9ASCN10A | |
| SCHEMBL4753092 | 0.78 | KIF11 (0.45) | GNRHRKIF11BRD4TLR7KDM4E | |
| SCHEMBL5754954 | 0.78 | KIF11 (0.43) | KIF11BRD4CYP3A4SCN9ASCN10A | |
| SCHEMBL5325935 | 0.78 | KIF11 (0.39) | GNRHRKIF11BRD4TLR7MAPT | |
| SCHEMBL4750950 | 0.77 | TLR7 (0.48) | GNRHRKIF11BRD4TLR7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147852-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-12-04 | — | — | WO | disclosed |