Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4092214 | 0.82 | KIF11 (0.47) | KIF11TLR7TDP1GNRHRPDE4A | |
| SCHEMBL4750950 | 0.81 | TLR7 (0.48) | KIF11TLR7TDP1GNRHRPDE4A | |
| SCHEMBL4753092 | 0.81 | KIF11 (0.45) | KIF11TLR7TDP1GNRHRKDM4E | |
| SCHEMBL4753081 | 0.79 | KIF11 (0.45) | KIF11TLR7TDP1GNRHRKDM4E | |
| SCHEMBL5246048 | 0.79 | KIF11 (0.44) | KIF11TLR7NPSR1 | |
| SCHEMBL5740657 | 0.79 | KIF11 (0.46) | KIF11TLR7 | |
| SCHEMBL4102093 | 0.71 | KIF11 (0.46) | KIF11TLR7TDP1GNRHRKDM4E | |
| SCHEMBL4092061 | 0.70 | PDE4A (0.61) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5248649 | 0.70 | KIF11 (0.45) | KIF11TLR7GNRHR | |
| SCHEMBL5250049 | 0.70 | KIF11 (0.43) | KIF11NPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147852-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-12-04 | — | — | WO | disclosed |