Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | POLR1A | O95602 | 3/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753081 | 0.86 | KIF11 (0.45) | KIF11MC4RTDP1KDM4EKMT2A | |
| SCHEMBL4750947 | 0.81 | KIF11 (0.45) | KIF11TDP1KDM4ENPSR1GNRHR | |
| SCHEMBL5248649 | 0.81 | KIF11 (0.45) | KIF11MC4RGNRHRTLR7BRD4 | |
| SCHEMBL5250049 | 0.81 | KIF11 (0.43) | KIF11MC4RMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4752599 | 0.79 | KIF11 (0.46) | KIF11KDM4EKMT2AMEN1NPSR1 | |
| SCHEMBL4102093 | 0.79 | KIF11 (0.46) | KIF11POLR1ATDP1KDM4EKMT2A | |
| SCHEMBL4753094 | 0.78 | GNRHR (0.41) | KIF11TDP1KDM4EKMT2AMEN1 | |
| SCHEMBL5754455 | 0.78 | MAPT (0.43) | KIF11MAPT | |
| SCHEMBL5754170 | 0.76 | KIF11 (0.43) | KIF11TDP1KDM4ESMN1; SMN2BRD4 | |
| SCHEMBL4750941 | 0.74 | TP53 (0.44) | MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147852-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-12-04 | — | — | WO | disclosed |