Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.73 |
| ▸ | HTR2A | P28223 | 4/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.73 |
| ▸ | HRH1 | P35367 | 4/20 | 0.73 |
| ▸ | DRD3 | P35462 | 4/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.73 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.73 |
| ▸ | DRD4 | P21917 | 3/20 | 0.73 |
| ▸ | DRD5 | P21918 | 3/20 | 0.73 |
| ▸ | HRH2 | P25021 | 3/20 | 0.73 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.73 |
| ▸ | HTR7 | P34969 | 3/20 | 0.73 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.73 |
| ▸ | HTR6 | P50406 | 3/20 | 0.73 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.73 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.73 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.73 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.73 |
| ▸ | HTR2C | P28335 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554386 | 0.80 | SLC6A3 (0.60) | SLC6A3HTR2AADRA1AHRH1DRD3 | |
| Hydrochloric Acid SCHEMBL10947777 | 0.80 | MEN1 (0.73) | SLC6A3HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL4752728 | 0.80 | CACNA1F (0.67) | SLC6A3HTR2AADRA1AHRH1DRD3 | |
| Hydrochloric Acid SCHEMBL10810457 | 0.80 | MEN1 (0.72) | SLC6A3HTR2AADRA1AHRH1DRD3 | |
| Hydrochloric Acid SCHEMBL10557900 | 0.79 | SLC6A3 (0.59) | SLC6A3HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL4753130 | 0.79 | HTR2A (0.69) | SLC6A3HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL5027722 | 0.79 | HTR2A (0.59) | SLC6A3HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL5077519 | 0.78 | HTR7 (0.67) | SLC6A3HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL5074793 | 0.78 | HTR7 (0.66) | SLC6A3HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL5077507 | 0.78 | CACNA1F (0.66) | SLC6A3HTR2AADRA1AHRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147864-A2 | METHODS OF USING PIPERAZINE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-12-04 | — | — | WO | claimed |
| WO-2008147864-A2 | METHODS OF USING PIPERAZINE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-12-04 | — | — | WO | disclosed |